The band is in its 46th consecutive year of touring and will stop in Evansville May 21.
Chicago is dedicating its 2014 tour to the wife of Notre Dame's football coach who is a breast cancer survivor and close friend to the band.
Tickets go on sale this February 28.
Also coming to Evansville is WWE. The show on April 27 is scheduled to have superstars like John Cena the Wyatt Family, and Daniel Bryan.
Tickets for that go on sale March 1.