The incident happened shortly after 1:00 Friday afternoon at the Carriage House Apartments on North Green River Road.
Officers arrested Darius Hamell, Derrick Mckinley, Keshaun Beckton and David Gray on charges stemming from the shots fired run.
Investigators tell us Hamell, Mckinley, and Beckton are wanted for questioning in a recent St. Louis homicide.
The resident of the apartment, Darrell Rhodes, was arrested on unrelated charges.
All four men are being held in the Vanderburgh County Jail on various charges.