Dispatch says a truck carrying plywood crashed at the end of the bridge at the Ohio and Muhlenberg County line around 12:30 Friday morning.
That is around the 65 mile marker,
Wood is all over the road blocking the East and Westbound lanes of the Parkway.
Detours on both sides of those counties are set up.
You can take the Beaver Dam exit in Ohio County and the 431 Central City exit in Muhlenberg.
Officials are saying this will be closed until at least 9 Friday morning.
The driver was taken to the hospital.
The cause of the crash is under investigation.