Democratic state Rep. John Arnold of Sturgis submitted a letter of resignation to Gov. Steve Beshear on Friday.
The resignation came just days ahead of the first meeting of a special legislative committee that's investigating the charges against Arnold. The panel was scheduled to meet on Tuesday, and could have ultimately recommended Arnold's censure or expulsion from the Legislature.
In the complaints, two female legislative workers alleged that Arnold had touched them inappropriately and had made vulgar comments.
Arnold hasn't publicly responded to the allegations. He didn't return a phone call to his legislative office Friday.