The incident started in Vanderburgh County as deputies say they attempted a traffic stop at Inglefield and Highway 41.
Central Dispatch says after the suspect refused to stop, a hgh speed chase followed, heading north on 41 to I-64 West.
The car is a 2002 gold Chevy Malibu with Michigan license plate BJC5858.
Law enforcement from Posey, Vanderburgh and Gibson Counties, as well as Indiana State police were involved in the chase, which has been called off.
We will bring you updated information as it becomes available.